Fetoprotein 48μg/L is not very serious. The normal reference value of alpha-fetoprotein ranges from 0 to 25 μg/L (the reference value range may vary depending on the testing method of the hospital you are in), and 48 μg/L suggests that the value of alpha-fetoprotein is mildly elevated. Alpha-fetoprotein is a tumor marker, mainly used to assist in the diagnosis of primary liver cancer and malignant tumors such as gastric cancer, pancreatic cancer, ovarian cancer and testicular cancer. In addition, during pregnancy, alpha-fetoprotein will increase to a certain extent, and its value changes are related to the growth and development of the fetus, and can also be used to assist in the diagnosis of intrauterine fetal death, neural tube malformation, anencephaly and spina bifida, and so on. Alpha-fetoprotein is a glycoprotein synthesized by the fetus and gradually decreases to undetectable after birth. However, if liver cells or embryonic tissues of the gonads (ovaries in females, testes in males) become cancerous, the synthesis of alpha-fetoprotein increases, resulting in elevated levels in the serum. Elevated alpha-fetoprotein is recommended to consult a doctor for diagnosis and treatment.