Anti-inflammatory drugs for toothache include nitroimidazoles, penicillins, cephalosporins, and macrolides, which can lead to gastrointestinal reactions, neurological symptoms, allergic reactions, liver and kidney function impairment, and other side effects. 1. Nitroimidazole anti-inflammatory drugs: such as metronidazole, ornidazole, etc. Common side effects include nausea, vomiting, loss of appetite, vertigo, polyneuritis and so on. 2. Penicillin anti-inflammatory drugs: such as amoxicillin, may appear dizziness, nausea, vomiting, rash, diarrhea and other side effects. 3. Cephalosporin anti-inflammatory drugs: such as cefixime, nausea, abdominal pain, diarrhea, skin rash, impaired liver and kidney function and other side effects. 4. macrolides anti-inflammatory drugs: such as acetylspiramycin, common side effects include nausea, diarrhea and so on. In the use of these drugs to treat toothache, must be strictly in accordance with the medical prescription under the guidance of the doctor to take, at the same time need to pay attention to the use of drugs during the contraindication.