Coronary angiography is an invasive operation and can cause certain injuries, such as allergy-induced skin rashes, laryngeal edema, kidney injury, and acute myocardial infarction. Coronary angiography is an effective method to diagnose coronary artery disease, but it is an invasive test that requires the use of anesthetics and contrast media, so it may cause skin rash, laryngeal edema, or even shock due to allergy, and the contrast media may lead to the occurrence of acute kidney injury, and improper operation may lead to acute myocardial infarction, and so on. In addition, bleeding or infection at the puncture site, or rupture of the arterial vessels due to improper handling may also occur. Patients who need coronary angiography should undergo it under the guidance of a doctor, actively cooperate with the doctor’s preoperative evaluation, and do not conceal their medical history, allergy history, and so on.