The causes of generalized soreness after fire cupping include normal reaction, which is related to the local negative pressure stimulation; it also includes abnormal reaction, such as local fire cupping time is too long, the body is too cold or weak, etc., which needs to be given symptomatic conditioning or treatment in time. 1. Normal reaction: fire cupping is mainly a local continuous negative pressure effect, to help regulate the body’s qi and blood flow, dredge the meridians and so on. Occasionally, after cupping, temporary generalized pain and discomfort may occur due to negative pressure stimulation, which is normal and usually does not require special treatment. 2. Abnormal reaction: Due to improper operation of fire cupping, prolonged negative pressure, excessive accumulation of cold in the body, or the body suffers from certain diseases, resulting in low immunity and the above symptoms. It is necessary to consult a doctor for diagnosis, and give symptomatic treatment according to the doctor’s instructions to avoid delaying the condition. It is recommended that fire cupping should be carried out in a regular medical institution to avoid blind operation leading to discomfort. At the same time, we should pay attention to avoid catching cold after fire cupping, maintain a light diet, etc., to eliminate adverse factors.