Nosintrol is the trade name for sacubitril valsartan sodium tablets. The heart does not usually get significantly smaller after one month of administration. Sacubitril valsartan sodium tablets can be used as an alternative to angiotensin-converting enzyme inhibitors or angiotensin II receptor antagonists for the treatment of chronic heart failure with reduced ejection fraction, thereby reducing cardiovascular mortality and hospitalization rates. Sacubitril valsartan sodium tablets have the potential to reverse ventricular remodeling and make the ventricles smaller or even return to normal in patients with relatively small myocardial infarctions or mild fibrosis when taken over a long period of time, but each person’s situation is different, so the recovery is also different. But taking one month is relatively short, so the heart is usually not significantly smaller. Sacubitril valsartan sodium tablets may cause angioedema, hypotension, renal impairment, hyperkalemia and other side effects, and are not recommended for patients with allergy to this drug, severe hepatic impairment, and mid- to late-stage pregnancy. Therefore, it is not recommended to take the drug by oneself, and must be taken under the guidance of a doctor. Blood pressure, renal function, electrolytes and other items also need to be monitored during the medication.