Mild proliferation of bone marrow fibers can appear to continue to worsen. When bone marrow fibers are in a mild stage, if effective measures are not taken in time, the proliferation of fibrous tissue will continue to increase and the hematopoietic function will continue to decrease. When bone marrow fiber enters the advanced stage, bone marrow failure may even occur, resulting in a severe decrease in the number of red blood cells, white blood cells, and platelets in the blood. Generally speaking, mild degrees of myelofibrosis do not cause the body to experience obvious discomfort symptoms. However, as the disease deepens, it may show symptoms such as severe anemia or bleeding, bone hardening, liver and spleen enlargement. Therefore, in order to prevent the disease from posing a threat to your health, you should go to the hospital as soon as possible for examination and treatment, and do not delay your condition by taking any chances. Myelofibrosis is a serious disease, so it should be taken seriously and diagnosed and treated early.