Safflower oil should not be used together with Yunnan Baiyao. The two drugs are used at separate times and have different functions and effects. Both drugs are used in the treatment of bruises, but in the early stage of the injury is the acute inflammatory response period, during which vascular exudation and swelling are evident, this is the right time to use Yunnan Baiyao, which can reduce vascular exudation and can eliminate swelling and relieve pain. For acute inflammatory reactions, the first 48 hours are generally in the ascending phase, and safflower oil is not suitable for this period. The role of safflower oil is to invigorate blood circulation, dissipate stasis and relieve pain, dilate blood vessels, promote blood circulation, and promote the remission of inflammation. If used to dilate blood vessels during the acute inflammatory period, it will aggravate vascular exudation, aggravate tissue swelling, and aggravate pain, so safflower oil is generally used for the treatment of 48 hours after injury, which can promote tissue healing.