Antiphospholipase A2 receptor antibody 576 is not normal. Usually the normal value of antiphospholipase A2 receptor antibody is <20, and it is a good predictor of the progression of membranous nephropathy. Antiphospholipase A2 receptor antibody is mainly used for the following clinical purposes: to identify primary and secondary membranous nephropathy; antibody titer and the degree of nephropathy are generally correlated; antibody titer decreases or even turns negative in patients with effective treatment, and then the nephropathy goes into remission; in relapse, antibody often turns positive first, and then the nephropathy relapses; the majority of patients conform to this pattern. Elevated anti-phospholipase A2 receptor antibody is recommended to go to the hospital in time, complete the examination under the guidance of specialists, make a clear diagnosis and timely treatment.