Mirtazapine can be used in the elderly, but it is recommended that patients strictly follow the doctor’s instructions for medication. Mirtazapine tablets are suitable for all kinds of depression, as well as the lack of pleasure, psychomotor inhibition, poor sleep and other symptoms are effective. Mirtazapine for Alzheimer’s patients is mainly to improve the symptoms, in addition to mirtazapine can also use donepezil, carboplatin, sarcosine A and other drugs, can increase the level of acetylcholine in the brain, strengthen the synaptic transmission. As the use of Mirtazapine in the elderly is more likely to lead to a decline in renal function, and there is also the possibility of confusion and over-sedation in the elderly, the dosage should be chosen with caution. The use of mirtazapine in the elderly should be under the guidance of a doctor. If accelerated progress or complications are found, prompt medical attention should be sought and regular checkups should be conducted as prescribed by the doctor to avoid adverse reactions. Older adults can exercise on a regular basis to help improve mood and keep joints, muscles, and the heart healthy; regular socialization can help seniors retain certain abilities.