Low immunity is a contributing factor to HPV infection, but it is not the determining factor in causing HPV infection. HPV infection is an infectious disease that can be transmitted through skin or mucous membrane contact as well as indirectly. The vast majority of people with condyloma acuminatum are infected through sexual contact. Common warts, filiform warts, flat warts, and plantar warts can be caused by scratching or tiny defects in the skin where the virus is planted. In a very small number of cases, the virus can be transmitted through contact with contaminated objects, as well as from mother to child and from medical sources. Although low immunity can lead to a higher likelihood of HPV infection, low immunity is not the direct cause of HPV infection, but direct and indirect contact with HPV-infected people is the main cause of HPV infection. Since HPV infection is highly contagious and has a higher likelihood of recurrence, and some patients may develop cancer, it is important to recognize the importance of preventing and treating HPV infection.