A big, red, swollen pimple can be treated with topical medication, oral medication, and dietary modifications. 1. topical medication: when the skin appears to be red and swollen pimples, you can use local anti-inflammatory ointment to smear, commonly used ointment mupirocin ointment, fusidic acid cream, clindamycin gel and so on. 2. Oral medication: Skin red acne symptoms are more serious or the effect of local medication is not ideal patients, it is recommended with oral anti-infective drugs, commonly used drugs are minocycline hydrochloride capsules, doxycycline hydrochloride tablets, clarithromycin capsules, and so on. 3. Dietary adjustments: when the skin appears red and swollen acne, pay attention to dietary adjustments, avoid greasy and spicy stimulating food, so as not to aggravate the symptoms of red and swollen acne. In daily life, we should pay attention to avoid eating spicy stimulation and greasy food, if the acne redness and swelling is serious, it is recommended that the patient timely consultation, by the doctor to give targeted treatment.