HPV54 positive indicates infection with human papilloma virus, which is a high-risk infection. If it is detected for the first time and the cervical fluid-based cytology is normal, it can be observed for six months first and then rechecked again after six months. If it is still positive, you need to apply antiviral drugs, such as interferon or transfer factor for treatment, and do cervical cancer screening at the same time of the next review, mainly to exclude the possibility of cervical cancer. HPV is divided into high-risk and low-risk types, and the high-risk type mainly causes cervical cancer in women. When infected with HPV, one may not necessarily feel uncomfortable, but may also experience erosion-like changes in the cervical area. When this occurs, measures must be taken to treat the condition under the guidance of a doctor, either by considering local vaginal medication or by considering physical therapy.