The difference between Dazhongyin Pill and Zhibai Di Huang Wan lies in the composition and main treatment. 1. Difference in composition: Dazhongyin Pill consists of ripened dihuang, vinegar tortoise shell, salt motherwort, pig spinal cord, salt cedar; Zhi Bai Di Huang Wan consists of motherwort, cedar, cornelian cherry, ripened dihuang, mudanpi, ze diarrhea, Chinese yam, Poria. 2. The difference between the main treatment: Dazhongyin Pill is mainly used for treating yin deficiency and fire (deficiency of yin and essence in the body, and hyperactive fire), cough, hot flashes (a burst of heat), night sweating (abnormal sweating after falling asleep, and sweating stops after waking up), tinnitus and spermatorrhea; Zhi Bo Di Huang Wan is mainly used for treating yin deficiency and fire, lumbar and knee soreness and tenderness (feeling of soreness and tenderness of lumbar and knee), hot flashes and night sweating, tinnitus, dry mouth and throat pain, spermatorrhea, and so on. Both are effective in nourishing yin and lowering fire (nourishing yin essence and lowering fire). The adverse reactions and contraindications of Da Tian Yin Wan and Zhi Bai Di Huang Wan are not known. If medication is needed, it should be consulted with a doctor first and taken under the doctor’s guidance to avoid improper use of medication and delay of the condition.