Folic acid tablets can be taken in the morning, at noon or at night. Folic acid tablets belong to the vitamin class of drugs, there is no clear scientific regulation on the time to take folic acid tablets, you can take them in the morning, or at noon or at night. Folic acid tablets can be used for the treatment of megaloblastic anemia caused by folic acid deficiency. Taking folic acid tablets during pregnancy can prevent neural tube malformations in the fetus. It can also be used for folic acid deficiency caused by chronic hemolytic anemia. Adverse reactions to folic acid tablets are relatively rare, allergic reactions are rare, long-term large quantities of folic acid tablets, may be bloating, nausea, fear of food and other adverse reactions, there may also be a dark yellow or yellow change in the urine. Megaloblastic anemia caused by vitamin B₁₂ deficiency alone generally cannot be treated with folic acid tablets alone. It is necessary to use folic acid tablets under the guidance of a specialized doctor, depending on the specific condition.