Porphyria, also known as osteogenesis imperfecta, is a genetic disorder that is a disorder of collagen formation and is clinically rare. The main clinical diagnosis is based on a diagnostic triad, such as dental hypoplasia, generalized severe osteoporosis leading to multiple fractures throughout the body, and blue sclera. Patients with osteogenesis imperfecta will have different degrees of osteoporosis throughout the body, which can easily lead to multiple fractures throughout the body, sometimes at birth. The main examination method is X-ray, which shows thin tubular bones (mainly in the limbs), reduced bone mass, reduced bone cortex, and curvature and other manifestations. There is no specific drug for osteogenesis imperfecta, and the main treatment is to give plaster, splint and brace fixation after fracture occurs, or surgery if there are multiple fractures throughout the body.