The ingredients of Zhenzhong Yiqi Pill and Si Jun Zi Pill are different, both of them can be used to treat the weakness of the spleen and stomach, but the efficacy of the main treatment is different. 1. The composition of Chinese medicine is different: the composition of the pill is roasted astragalus, ginseng, roasted licorice, atractylodes macrocephala, angelica, sesame, chaihu, chenpi. Four Gentlemen Pill is composed of ginseng, atractylodes macrocephala, Poria, roasted licorice. 2. Difference in efficacy and main treatment: tonifying the middle and benefiting the qi pill efficacy for tonifying the middle and benefiting the qi, ascending and lifting the sun. It is used for the weak spleen and stomach, Qi subsidence (deficiency of spleen and stomach Qi, visceral organs falling and other manifestations) caused by tiredness and fatigue, less food and abdominal distension, loose stools (feces thin and not shaped), prolonged diarrhea, anus falling. The efficacy of Sijunzi Pill is to benefit qi and strengthen the spleen (regulating the qi of the spleen and stomach). It is used in treating deficiency of spleen and stomach qi, poor appetite and loose stools. Both of the above proprietary Chinese medicines need to be selected and used under the diagnosis and treatment of a Chinese medicine practitioner.