The causes of itching all over the body in the fifth month of pregnancy may be related to skin allergies, or may be due to urticaria, intrahepatic cholestasis in pregnancy and other causes. 1. Skin allergies: commonly found in allergic individuals, due to the consumption of certain foods or contact with certain substances, may cause a generalized allergic reaction, which may result in five months of pregnancy itchy, may also be accompanied by localized body rashes. 2. Urticaria: It is mostly considered that it may be caused by viral infection, physical stimulation, endocrine and mental factors, etc. Stimulation by the above factors during the fifth month of pregnancy is likely to induce urticaria, which may cause generalized itchiness, and may be accompanied by localized skin tingling, lesions and other symptoms. 3. intrahepatic cholestasis in pregnancy: usually associated with estrogen level changes, environmental factors, genetic factors, especially in the fifth month of pregnancy, due to the pregnant woman’s body in the estrogen level rises, affecting the function of the liver cells, hindering the synthesis of bile, resulting in intrahepatic cholestasis in pregnancy, which can cause itchy all over the body. Itchy body in the fifth month of pregnancy may also be caused by other reasons, it is recommended to consult a doctor as soon as possible, after a clear diagnosis, by the doctor’s guidance treatment and adjustment.