Whether patients with celiac disease can take clopidogrel depends on the specific condition. Clopidogrel is a platelet antagonist, which can play a role in inhibiting platelet aggregation; clinically, it can be used to treat myocardial infarction, ischemic stroke, peripheral arterial disease and so on, as well as to prevent thrombosis of atherosclerosis. This drug should not be used in patients with hypersensitivity to the product, active pathological bleeding (such as peptic ulcer, intracranial hemorrhage), severe liver damage. In patients with gastric erosion, if it is mild and there is no active bleeding, clopidogrel can be taken, along with acid-suppressing drugs (omeprazole), gastric mucosal protectors (thioglycollate) for the treatment of the condition of gastric erosion. In case of severe erosion with history of ulcer and higher risk of bleeding, it is necessary to combine with the patient’s cardiac condition, and under the overall guidance of the doctor, reduce the dosage or discontinue or change the medication as appropriate, and at the same time, closely monitor the changes in the condition and adjust the treatment program in time. Clopidogrel medication may be non-serious bleeding, drug rash, colitis, granulocyte deficiency, hepatitis and other adverse reactions. It is recommended to stop the drug immediately if blood in the stool occurs during treatment. Patients with gastric celiac disease who need to use clopidogrel should be treated under the strict guidance of a doctor and in accordance with medical advice.