Taking sodium bicarbonate for rhabdomyolysis usually works. Sodium bicarbonate alkalizes the urine, corrects metabolic acidosis, and prevents hyperkalemia. Sodium bicarbonate may be used intravenously if oral sodium bicarbonate does not achieve efficacy. Rhabdomyolysis syndrome is a series of symptoms, such as myalgia, limb weakness, and tea-colored urine, caused by damage to the rhabdomyocytes and the release of substances from the muscle cells into the circulation. Rhabdomyolysis can cause the body’s internal environment to become acidic, leading to an increase in the concentration of potassium ions in the circulation and promoting the deposition of substances such as uric acid and myoglobin. Sodium bicarbonate can be applied for neutralization, which plays a role in maintaining acid-base balance, relieving hyperkalemia, and promoting the excretion of uric acid, myoglobin and other substances. If oral sodium bicarbonate does not achieve the therapeutic effect, sodium bicarbonate can be used intravenously. If patients apply sodium bicarbonate is recommended to use the drug under the guidance of a doctor, not blindly self-medication, in order to avoid adverse effects. Patients with rhabdomyolysis are advised to go to a regular hospital in time to be treated under the guidance of a doctor.