The treatment of cutaneous neurodermatitis includes general treatment, topical and systemic medication, physical therapy and so on. 1. General treatment: daily life should pay attention to the care of the affected area, avoid scratching, friction and other stimuli, supplemented by psychological treatment, to stop the vicious cycle of “itching-scratching-itching”. 2.Drug treatment (1) Topical medication: commonly used medications include Denadyl cream, dexamethasone cream, tacrolimus ointment and other medications for treatment. Some patients can also be treated with local sealing or intradermal injection of glucocorticoid drugs such as prednisone. (2) Systemic medication: antihistamines such as loratadine, calcium, vitamin C, vitamin B and glutamine are commonly used. Those who affect sleep can use diazepam, doxepin and other drugs as appropriate. Severe cases can be used for intravenous closure with procaine, and those with generalized skin lesions can take oral tretinoin tablets and so on. 3. Physical therapy: phototherapy can be applied to those with generalized lesions. It is recommended to consult a doctor in time for diagnosis and treatment. The use of specific drugs should be under the guidance of the doctor.