The treatment of knee weakness depends on the cause and course of the disease, as well as the combination of diseases and complications, the patient’s age, personal constitution, and other factors. If there is a sudden onset of knee weakness, it is mostly related to incorrect exercise. If you do not see any relief after rest, you should go to the orthopedic department or neurology or rheumatology department of the hospital, and the doctor will conduct relevant examinations according to the symptoms and signs to clarify the cause and deal with it accordingly. If the knee joint is caused by traumatic strain, patellar tenderness, etc., it needs to be treated by an orthopedic surgeon according to the situation. If it is rheumatoid arthritis, anti-infection immunotherapy should be administered. Symptomatic treatment includes rest and braking, local heat application, physical therapy, Chinese medicine, acupuncture, massage, tui-na and other treatment modalities. It is necessary to develop an appropriate treatment plan according to the condition under the guidance of a doctor.