Vomiting large amounts of dark red blood is commonly associated with peptic ulcers, including gastric ulcers and duodenal bulb ulcers, which account for about 40% of upper gastrointestinal bleeding. Another cause of bleeding is acute gastric mucosal lesions, such as taking NSAIDs like aspirin and drinking alcohol, etc. Acute gastric mucosal lesions can cause vomiting of large amounts of dark red blood. Cirrhosis, rupture of esophagogastric fundic varices, usually with a history of chronic cirrhosis, will repeatedly bleed and bleed heavily. There is also gastric cancer. Patients with gastric cancer will vomit large amounts of dark red blood, the incidence of which is relatively small but often encountered clinically, and can be clearly diagnosed by gastroscopy.