Cranial repair surgery is a common brain surgery for repairing the skull in response to traumatic brain injury and cerebral defects that lead to cranial defects. Cranial defects not only affect the aesthetics, but also the patients often have a heavier sense of insecurity and other ideological burdens, and even cause cranial defect syndrome, intracranial pressure instability and other related problems, the longer the cranial defect is, the higher the incidence of cranial defect syndrome and secondary brain damage, which seriously affecting the patient’s life and work. The main purposes of cranial bone repair surgery are: 1. Improve the blood circulation of brain tissue. 2. Improve cerebrospinal fluid circulation of brain tissue. Release the adhesion of brain tissue at the cranial defect. 4.Maintaining the stable pressure of brain tissue from changing with external air pressure. 5.Improve the appearance of the patient’s skull. 6.Relieve or eliminate the patient’s cranial defect syndrome, which is mainly manifested as: headache, dizziness, agitation, anxiety, fear, and inattention. Cranial bone repair surgery is generally selected materials are titanium mesh and polyether ether ketone materials. Among them, polyether ether ketone – peek material is the most suitable choice for cranial bone repair material, peek material compared to earlier materials, more stability, it is a polymer material, elasticity, stability, heat insulation, and can also be shaped according to the different patient’s situation in three dimensions, the effect of the post-surgery with a normal person. After the surgery, the result will be the same as a normal person, which is the ideal material for cranial bone repair at present.