Taking amoxicillin has no effect on urination. Amoxicillin is not metabolized after it is absorbed into the body, and is excreted from the urine directly in its original form through glomerular filtration or renal tubular secretion, so the concentration of active amoxicillin in the urine is very high. Although amoxicillin is excreted through urine, it has no effect on kidney function and no effect on urination, so it can be used safely. Amoxicillin is an oral antibacterial drug commonly used in clinical practice and has very good effects on both sensitive gram-negative bacilli and gram-positive cocci, and can be used to treat infections of the respiratory tract, or genitourinary tract, as well as infections of the soft tissues of the skin. Although amoxicillin is excreted through the kidneys and through the urine, it has no effect on urination and can be used safely. However, it should be noted that the use of amoxicillin is contraindicated in people with penicillin allergy.