Bile refers to the gallbladder. Gallbladder discomfort refers to a lesion of the gallbladder, which may cause pain, gastrointestinal discomfort, fever, and other symptoms. 1. Pain: A gallbladder lesion may cause pain in the right upper abdomen, which may also manifest as radiating pain in the back of the right shoulder. The pain may be vague and uncomfortable or severe and colicky. 2. Gastrointestinal discomfort: a bad gallbladder will affect the body’s digestive function, leading to nausea, vomiting, bloating, indigestion and other gastrointestinal symptoms in most patients. 3. Fever: some serious patients, such as acute cholecystitis or combined with infection and suppuration, will have fever, body temperature can even reach 40 ℃. When the patient’s gallbladder is uncomfortable, there can also be weakness, loss of appetite, jaundice and other symptoms, it is recommended that the patient seek medical attention in time to do the relevant examination and active treatment.