The amount of cerebrospinal fluid (CSF) drained, in general, is about 400-500 ml per day, and if the patient has hydrocephalus or increased intracranial pressure when doing lumbar puncture, the amount of cerebrospinal fluid can be appropriately put more, but it is not recommended to overdo it, and if the amount of cerebrospinal fluid drained is more than 100 ml per time, in severe cases, people may have low cranial pressure headache or the risk of cerebral herniation, so it is recommended not to exceed 100 ml per time. It is recommended that the volume of cerebrospinal fluid (CSF) should not be more than 100 ml. For routine lumbar puncture examination, it is recommended that the volume of cerebrospinal fluid (CSF) should be around 20 ml per examination, and routine biochemical examination should be done after the CSF is collected. Cerebrospinal fluid is mainly found in the cerebral ventricles and subarachnoid space, it is colorless and transparent, and has a protective, supportive and nutritive effect on the brain and spinal cord. If too much cerebrospinal fluid is drained at one time, a person can develop this intracranial hypotension syndrome. The normal cerebrospinal fluid pressure is at 80-180 mmH2O, when the intracranial pressure is lower than 60 mmH2O, the person develops this lowered intracranial pressure, and in severe cases this headache, dizziness, nausea, and vomiting can occur.