The types of drugs used in heart failure treatment have no relationship with age, mainly cardiotonic, diuretic, vasodilator, β-blocker and other drugs to improve the long-term prognosis, whether it is 30 years old, 40 years old, or 80 years old, there is no difference in the types of drugs, the main consideration in the use of medication is not the age of the patient, but the patient’s vital signs, the function of the organs, and so on. Heart failure medication, oral cardiotonic drugs such as digoxin, diuretic drugs such as furosemide, torasemide, etc., vasodilators such as nitrate drugs, drugs to improve long-term prognosis of spironolactone, β-blocker metoprolol, angiotensin-converting enzyme inhibitor enalapril, angiotensin receptor antagonists such as temsiartan and so on, and shakubutra valsartan and so on. All of these drugs can theoretically be taken orally by 80-year-old patients with heart failure, and what needs to be paid attention to in the process of oral intake is blood pressure, heart rate, liver and kidney function, electrolytes, etc. Therefore, the treatment of patients with heart failure needs to be carried out under the guidance of specialized doctors in cardiology, and needs to be regularly reviewed in the Department of Cardiology.