Cerebral infarction patients with toothache may be caused by inflammatory diseases such as apical periodontitis, you can take metronidazole to control the inflammation, but also may be caused by dentin hypersensitivity, pulpitis, cryptic fissure and other diseases, taking metronidazole has no therapeutic effect, as follows. 1. Inflammatory diseases: metronidazole has a strong killing effect on anaerobic bacteria, and has a therapeutic effect on inflammatory diseases caused by anaerobic bacterial infections, such as apical periodontitis. Cerebral infarction is not a contraindication to metronidazole, so patients with cerebral infarction can take the drug. The drug should be used under the guidance of a doctor and should be combined with root canal treatment to completely eliminate inflammation. 2. Non-inflammatory diseases: such as dentin hypersensitivity, cryptocleidosis and other inflammatory diseases not caused by bacterial infection, taking metronidazole has no therapeutic effect, and dentin desensitization and filling treatment should be carried out respectively. Endodontitis when the effect of systemic medication is not obvious, also do not have to take metronidazole. There may be other reasons for toothache in patients with cerebral infarction, so it is recommended to go to the hospital in time to receive professional treatment.