The twisted deformation of the face is considered to be facial nerve paralysis, facial muscle spasm, accidental injury, etc., and should be treated for the cause. 1. Facial nerve palsy: facial nerve injury will appear facial muscle paralysis, such as crooked corners of the mouth, nasolabial folds become shallow, eye fissure, and other symptoms, serious loss of facial expression. It should be treated according to the cause, for example, for viral infection can be antiviral treatment, at the same time, acupuncture, massage, massage, physiotherapy, etc. to promote recovery. 2. Facial muscle spasm: there will be unilateral facial muscles paroxysmal involuntary twitching, emotional tension or excitement when the symptoms will be more obvious, and even crooked corners of the mouth. You can take carbamazepine, oxcarbazepine and other drugs to relieve spasm, but also through surgery to relieve compression. 3. Accidental injury: crash, burns and other accidental injuries will damage the facial soft tissues, nerves, bones, and the damage is serious and can not be restored to the normal state. It can be treated by plastic and cosmetic methods. The face is twisted and deformed, should promptly seek medical attention, clear cause, follow the doctor’s instructions for treatment.