Gastroesophageal reflux disease is clinically more common, has a longer duration and is easily recurrent. With timely treatment and regular therapy, symptoms can be relieved and cured, but attention must be paid to dietary regimen and correction of poor lifestyle habits. Gastroesophageal reflux disease (GERD) is a disease in which the stomach contents flow back into the esophagus causing symptoms and/or complications such as heartburn, acidity and chest pain. According to the data, the prevalence of GERD is higher in western countries, and the prevalence of GERD can reach 20-30% in the adult population, with about 7% of adults having reflux once a day. In 2005, the incidence of GERD in China was 6.7%, and the incidence of the disease is on the rise in both the West and Asia, and there is a tendency of youthfulness, some patients are easily neglected and cannot be treated in time, making the disease worse. Since this disease is easily confused with chronic pharyngitis, gastritis, lung disease, cardiovascular disease, etc., some patients are often seen in the Department of Five Gases due to foreign body sensation in the throat; some are seen in the Department of Respiratory Medicine due to chest pain; some are seen in the Department of Cardiology due to left anterior chest pain, suspected to be angina pectoris, so it must be differentiated through various examinations. Western medicine treatment is mainly by inhibiting gastric acid secretion and improving gastric power. In Chinese medicine, the identification of the disease belongs to the categories of “acidity”, “regurgitation”, “noisy”, etc. According to the theory of Chinese medicine, “the spleen should rise to be healthy, the stomach should descend to be harmonious”. “Stomach Qi is the basis for the storage, digestion and transmission of food and drink. Because of liver qi offending the stomach, internal heat, or improper diet, too much spicy food, etc., can lead to the stomach qi should be lowered but not lowered, so that the stomach contents reversed upward, resulting in a series of symptoms such as panacidity, heartburn, pain behind the sternum. We take advantage of the advantages of traditional Chinese medicine and formulated the formula of “Descending and Stomach Harmony”, which is based on the treatment of GERD by clearing heat and stomach, stopping acidity and lowering rebellion, and has achieved good efficacy in clinical practice. “The composition of the formula is based on the ancient formula of Zuo Jin Wan, Xuan Fu Dai Ochre Tang and Xiang Su Drink with the addition and reduction of Wu Bei San. In addition, for difficult cases, a combination of Chinese and Western medicine can be used. In conclusion, gastroesophageal reflux disease is clinically more common, with a longer duration and easy to recur, as long as timely treatment, regular treatment, can relieve the symptoms and cure, but must pay attention to the regulation of diet and correct bad habits. The main methods are as follows: 1, regular and quantitative feeding, diet should be light (or eat less and more meals), dinner should not be full, 4 hours before bedtime should not eat. 2, reduce fat intake, cooking should be boiled, stewed, braised mainly, not fried. 3, quit smoking and alcohol. 4, less acidic drinks and sweets, such as lemon juice, chocolate, etc. 5, avoid spicy, stimulating, cold and indigestible food. 6, increase protein intake, such as lean meat, egg whites, milk, soy products, etc.