The side effects of long-term consumption of alfacalcitol are gastrointestinal tract, circulatory system, psychoneurological system, etc. and are usually accompanied by other adverse reactions. 1. Gastrointestinal tract: lack of appetite, belching (hiccups), vomiting, nausea, stomach upset, dyspepsia, abdominal distension. Rarely thirst, stomach pain. 2. Circulatory system: slight increase in blood pressure, rare palpitations, etc. 3. Psychoneurological system: heaviness of head, headache, insomnia, weakness of limbs, agitation, etc. Rarely drowsiness, chest pain, back pain, shoulder pain, tinnitus, memory loss. 4. Other adverse reactions: itching of the skin, rash, conjunctival congestion, periarticular calcification in a few patients. Allergic to vitamin D and its analogs, patients with hypercalcemia are prohibited. It is not suitable for pregnant women. The drug should be taken under the guidance of a doctor, and if any discomfort occurs, seek medical advice promptly.