The causes of heartburn are categorized into physiological factors and pathological factors. 1. Physiological factors: Eating too full, too cold, stimulating food and mental tension may cause heartburn. 2. Pathological factors: esophageal diseases such as esophageal ulcer, sliding diaphragmatic hernia, reflux esophagitis, Barrett’s esophagus, etc., gastric and duodenal diseases such as pancreatic cancer, peptic ulcer, gastritis, pancreatic surgery, etc., as well as gallbladder diseases such as cholecystitis, cholelithiasis, etc., can cause heartburn and heartburn. The symptoms of heartburn, heartburn, need to go to the hospital as soon as possible, under the guidance of a professional physician to clarify the cause of the disease, and targeted treatment, so as not to delay the condition.