Newborns cry every time before peeing, consider that it may be normal physiological factors, such as reflex discomfort before urination, physiological prepuce, etc., but also may be caused by urinary tract infection, vulvar eczema and other pathological factors. 1.Physiological factors: (1) Reflex discomfort: newborns crying before urination may be caused by reflex discomfort, such as a slight feeling of distension in the abdomen before urination, which is usually relieved after urination. (2) physiological prepuce: after the birth of newborns, some male infants will appear the foreskin wrapped around the head of the penis, the head of the penis and the foreskin adhesions between the phenomenon of physiological prepuce, urination will appear difficult to urinate, urine flow is slow, pain in the foreskin and other symptoms, which in turn caused the newborn to cry before urination. 2. Pathologic factors: (1) urinary tract infection: may be due to the male newborn congenital urinary tract abnormalities or urination after the failure to change the diaper in a timely manner leading to neonatal infection, symptoms of redness, swelling and pain of the vulva or penis, fever, pain in urination, pain in the lower abdomen, etc., so every time before urinating will stimulate the local skin to cause pain caused by the neonate crying. (2) Vulvovaginal eczema: it may be caused by the low resistance of the newborn or improper cleaning after urination, etc. Symptoms include vulvar itching, pimples, scratches with hyperpigmentation, and vulvar pain. The pain is aggravated when the newborn urinates, so it leads to crying before urination. Newborns cry every time before peeing, there may also be other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to determine the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.