At present, there are no clinical cases of constipation after taking Potassium Chloride Extended-Release Tablets, constipation may be caused by slow colon transmission, defecation disorders and intestinal diseases. Potassium chloride extended-release tablets, an electrolyte balance regulator, is mainly composed of potassium chloride. It is often used for the treatment and prevention of hypokalemia, digitalis intoxication causing frequent, multiple premature beats or tachyarrhythmias. Common adverse reactions after taking the drug include nausea, vomiting, abdominal pain, diarrhea, etc., but constipation does not usually occur. Constipation is mainly due to lack of dietary fiber intake as well as lack of exercise, overuse of medication, and pregnancy. Constipation may also be caused if the patient has weak muscle strength in the pelvic region. In addition, patients with intestinal disorders often experience constipation, such as colon tumors and narrowing of the intestinal lumen. To summarize, if the patient has serious constipation, it is recommended to go to the hospital in time to clarify the cause and target the treatment.