The treatment of whooping cough in adults includes general treatment, cough suppression, antimicrobial therapy, adrenocorticotropic hormone and high potency immunoglobulin therapy, and treatment of complications. 1. General treatment: isolation, keep the room quiet, fresh air and appropriate temperature and humidity. 2. Cough suppressant: spasmodic cough can be given to severe sedatives, such as sodium phenobarbital, diazepam and so on. Albuterol can also reduce cough, can be tried. 3. Antimicrobial therapy: antibiotics can be used, such as erythromycin, erythromycin and so on. 4. Adrenocorticotropic hormone and high efficiency immunoglobulin treatment: severe patients can apply prednisone, can reduce symptoms, can also apply high efficiency immunoglobulin, can reduce the number of spasm cough and shorten the spasm cough period. 5. Treatment of complications: (1) pulmonary atelectasis: postural drainage can be taken, and the blocked secretion can be discharged by fiberoptic bronchoscope if necessary. (2) convulsions: pertussis encephalopathy convulsions can be applied to sodium phenobarbital or diazepam. (3) Cerebral edema: intravenous mannitol when cerebral edema occurs. Pertussis patients should not self-medication, should go to the hospital in a timely manner, under the guidance of the doctor standardized treatment.