The best time for hyperbaric oxygen therapy for hemiplegic patients is when the patient’s vital signs and condition are stabilized, and it is better to carry out the treatment as early as possible. The addition of hyperbaric oxygen therapy is conducive to improving the patient’s motor function and ability to perform activities of daily living, accelerating the early recovery of the patient, and can play an important role in improving the quality of life of patients with the disease. As for the timing of hyperbaric oxygen intervention, it is believed that hyperbaric oxygen therapy should be used as early as possible along with conventional treatment, and the earlier the use of hyperbaric oxygen therapy, the better the effect, which is more conducive to the patient’s recovery and improves the efficiency of treatment. It is recommended that hemiplegic patients undergo hyperbaric oxygen therapy under the guidance of doctors and therapists to formulate a detailed diagnosis and treatment plan.