Side effects of Metformin Hydrochloride Enteric Tablets include loss of appetite, nausea, vomiting, rash, fatigue, and liver impairment. Metformin hydrochloride enteric-coated tablets belong to the western medicine, can be used for the treatment of type 2 diabetes mellitus with unsatisfactory dietary control alone; it is also effective for some patients with poor efficacy of sulfonylurea; it can also be used for patients with insulin treatment, which can reduce the dosage of insulin. Some people will experience side effects after taking metformin hydrochloride enteric-coated tablets, common side effects include loss of appetite, nausea, vomiting, skin rash, fatigue, etc. If the side effects are mild, there is no need to stop using the drug. If the side effects are mild, there is no need to stop using the medicine. If the side effects are serious, it is recommended to stop using the medicine and treat with other medicines. Contraindications of metformin hydrochloride enteric-coated tablets include severe heart and lung disease patients are prohibited; type 2 diabetes mellitus with ketoacidosis, acidosis, hepatic and renal insufficiency is prohibited; diabetes mellitus combined with severe chronic complications is prohibited, and so on. Metformin hydrochloride enteric-coated tablets should not be used privately, need to be combined with specific medical conditions, under the guidance of a professional doctor.