With the efficacy of inducing fire to return to the kidney (inhibiting the rise of fire evil in the kidney), warming Yang and submerging Yang, Submerged Yang Sealing Medulla is used for treating skin diseases caused by deficiency fire upflaming. Submerged Yang Seal Medulla Pellet is composed of Radix Aconiti, Radix et Rhizoma Serratiae, Radix et Rhizoma Glycyrrhizae, Radix et Rhizoma Glycyrrhizae, Rhizoma Cyperi, and has the effects of warming yang and submerging yang, returning qi to the kidneys, and assisting yang and warming the kidneys, and is mainly used in treating diseases caused by the upward inflammation of deficient fire, and the upward transference of deficient yang (a relative deficiency of yang affecting the head and face). According to the theory of Chinese medicine, Yin Yang Seal Marrow Dan can treat skin diseases such as mouth ulcers and urticaria caused by the inflammation of deficiency fire. Since Submerged Yang Sealing Marrow Dan contains epiphyllum, it is not recommended for patients who are allergic to this medicine. Patients with skin diseases are advised to go to regular hospitals for treatment under the guidance of professional physicians.