The price of one 23-valent pneumococcal polysaccharide vaccine is about $200-300. This vaccine is mainly indicated for the prevention of pneumococcal disease in community-acquired pneumonia and is given to people at high risk. For pneumococcal vaccine, it is generally used in people over two years of age. This vaccine contains a mixture of podococcal polysaccharides of 23 prevalent, relatively invasive Streptococcus pneumoniae species. Some people experience relatively few adverse reactions after vaccination, which may include localized redness, swelling, pain, sclerosis, and decreased mobility of the extremities at the injection site. Rarely, cellulitis may occur, and fever, nausea, vomiting, and allergy may also occur. People who are allergic to this vaccine are prohibited from receiving it.