The methods of gallstones discharge, mainly including drugs, surgery, endoscopy and so on. 1. Drugs: mainly use choleretic drugs for relief, such as deoxycholic acid tablets, ursodeoxycholic acid tablets, etc., which can promote bile discharge and control inflammation, the main purpose of which is to prevent the recurrence of biliary stones, although the effect of lithotripsy for stones that have already been formed is poor. 2. Surgery: including open surgery and laparoscopic cholecystectomy. Among them, open surgery is suitable for most patients with symptomatic gallstone disease and is the treatment of choice for patients with complications; while laparoscopic cholecystectomy is mainly used as a standard treatment for symptomatic gallstone disease and acute and chronic cholecystitis. 3. Endoscopic treatment: For patients with choledocholithiasis who cannot tolerate surgery, endoscopic duodenal papillotomy can be used for stone extraction, but it is forbidden to use it for patients with bleeding tendency and coagulation disorders. Due to the differences in individual conditions, specific methods of stone removal should be used reasonably under the guidance of a professional doctor and in conjunction with the patient’s condition.