Rosuvastatin different manufacturers can be mixed if they meet the criteria, but it is recommended not to change manufacturers frequently. The main effect of Rosuvastatin is to lower cholesterol, and the main clinical indications are for the treatment of hypercholesterolemia, and for patients with high-risk risk of ischemic cardiovascular and cerebral vascular disease, who also need long-term oral statin therapy. There are many manufacturers producing Rosuvastatin, as long as it meets the national production standards, the mechanism and degree of action of the same dose of the drug is the same, it is best not to mix drugs from different manufacturers, and patients are not advised to change the manufacturer of the drug frequently. Patients may experience some adverse reactions during oral administration of Rosuvastatin, such as nausea, muscle aches, dizziness, elevated liver enzymes, etc. It is contraindicated for patients who are allergic to the drug components, have severe hepatic impairment, or have unexplained elevated liver enzymes. When patients take Rosuvastatin orally, they should use the drug under the guidance of a doctor and avoid self-medication.