To determine the benign or malignant nature of renal adenoma, it is mainly judged by imaging examination, blood test and pathological biopsy. 1. Imaging examination: Generally, benign adenoma has smooth edges, homogeneous tissue composition, no obvious damage to the surrounding tissues and outward expansive growth; malignant adenoma has irregular edges, irregular morphology, mixed tissue composition, damage to the surrounding kidneys and mainly infiltrative growth. 2. Blood test: blood test is mainly to check the tumor marker, most of the tumor marker indexes of benign adenoma will not appear obvious abnormality; while the tumor marker of malignant adenoma may appear obvious increase, but the tumor marker test is not specific, normal may also exist malignant, and the abnormality may not be malignant, it is necessary to combine with other examinations to judge comprehensively. 3. Pathological biopsy: benign adenoma pathological biopsy is mainly composed of benign adenoma cells; malignant adenoma pathological biopsy will find disorderly cell proliferation, abnormal nuclear schizophrenia, etc. Basically, it can be clear that adenomas are benign or malignant through pathological examination. If you find that renal occupation is accompanied by obvious back pain and hematuria, you need to consult a doctor in time for observation, and carry out standardized treatment under the guidance of the clinician after diagnosing the condition, so as to avoid the delay of the condition.