A urine protein test result of a plus sign is usually positive for urine protein and is not normal. However, there are some normal physiologic conditions that may also result in positive urine protein. Usually, like having strenuous exercise or eating a high protein diet, or overexertion, normal physiologic proteinuria can occur. When women are pregnant, some may also develop physiologic proteinuria. It is usually normal and occurs for a short period of time. As soon as these conditions are corrected, the urinary protein will usually shift. If the persistent urinary protein is a plus sign, it suggests that there may be kidney lesions, leakage of proteinuria, possibly nephritis or other kidney disease. Like hypertension caused by kidney disease or diabetes caused by kidney disease, may appear positive proteinuria. Specific need to be combined with other tests to clarify what exactly is the cause, but also need to be combined with the clinical history, specific analysis of urine protein is caused by what.