There are differences in composition, efficacy and effects between Jin Gui Ren Qi Wan and Liu Wei Di Huang Wan. 1. Composition: Jin Gui Kidney Qi Pill consists of Dihuang, Chinese yam, Cornu Cervi Pantotrichum, Poria, Mudan Pi, Zedoaria, Gui Zhi, Pseudostellariae, Achyranthes Bidentata, Psyllium Heterophyllum, Psyllium Chebulae, and so on, while Six-flavored Digiton Pill consists of Radix Rehmanniae Praeparata, Chinese yam, Cornu Cervi Pantotrichum, Poria, Zedoariae, and Mudan Pi. 2. Efficacy: Jin Gui Ren Qi Pill has the efficacy of warming and tonifying kidney yang (warming and tonifying kidney yang qi), transforming qi to move water (promoting the operation of water and qi), focusing on tonifying kidney yang, and Liu Wei Di Huang Wan has the efficacy of nourishing yin and tonifying kidney, focusing on tonifying kidney yin. 3. Role: Jin Gui Ren Qi Pill is used for kidney deficiency and edema, lumbar and knee soreness and weakness (the feeling of lumbar and knee soreness and weakness), dysuria (unsmooth urination), chills and cold limbs (fear of cold, cold limbs), and Liu Wei Di Huang Pill is used for kidney yin deficiency, dizziness and tinnitus, lumbar and knee soreness and weakness, bone vaporization and tidal fever (a burst of heat, feeling the heat coming from the bone inside and outward), and seminal emission, etc. It is contraindicated for pregnant women. Jin Gui Kidney Qi Pill is contraindicated in pregnant women, and the use of the drug is contraindicated in the form of atrial lust, anger, and avoiding raw and cold foods. Liuwei Di Huang Pill should not be taken with cold medicine, avoid spicy and stimulating food, allergy is prohibited, during the use of the drug appeared in the stomach and stomach discomfort, abdominal pain and other symptoms to stop the drug in time to seek medical attention. The use of medication should be carried out under the guidance of a doctor, do not recommend self-medication.