There is no such thing as the most effective treatment for neonatal flatulence, and different measures need to be taken depending on the cause. Neonatal flatulence can be caused by physiologic factors, neonatal infections, and lactose intolerance, and can be improved with general treatment, cefixime, and other medications. 1. Physiological factors: Inadequate feeding of newborns, such as breastfeeding when crying or feeding too much milk at one time can lead to flatulence, just need to adjust the feeding program, scientific feeding can be. 2. Neonatal infections: When a newborn has a bacterial or viral infection, it may affect the gastrointestinal tract, leading to flatulence and slow bowel movements. It is necessary to take scientific treatment according to the pathogen of infection. Bacterial infections can be treated with anti-infections such as cefaclor. 3. Lactose intolerance: flatulence, hiccups, diarrhea, abdominal pain, crying and restlessness can occur, and can also cause flatulence in newborns. Lactase is usually used to relieve the symptoms. There are other causes of flatulence in newborns, so it is recommended to consult a doctor to identify the cause and treat it. The above medication should be used in accordance with the doctor’s instructions.