Severe hiccups require physical therapy or medication depending on the cause and symptoms. Physical therapy, such as abdominal hot packs, clockwise massage, walking and other appropriate activities are used for hiccups caused by gastric insufficiency, prolonged breath holding, pulling the tongue, pressing the carotid sinus are used for hiccups caused by diaphragmatic spasm, and drugs such as domperidone, omeprazole and other medications are used for hiccups caused by insufficiency of gastric power resulting in gastric upward movement and slow gastric peristalsis. In addition, hiccups may also be caused by esophagus, lungs and other parts of the occupied lesions stimulate the phrenic nerve, need to improve the relevant laboratory tests, if necessary, to carry out surgical treatment. Therefore, hiccups need to be based on different causes, choose different treatment options, patients can carry out physical therapy, but also under the guidance of a professional physician for drug therapy, avoid taking medication on their own, so as not to cause serious consequences, if the self medication appears to be significantly uncomfortable, it is recommended that the patient consult a doctor in a timely manner, so as not to cause serious consequences.