The difference between hepatitis E and hepatitis B: First, their pathogenesis is different, hepatitis E is liver damage caused by hepatitis E virus infection, hepatitis B is liver damage caused by hepatitis B virus infection. Hepatitis E is mainly transmitted through the fecal-oral transmission, that is, the digestive tract, while hepatitis B is mainly transmitted through blood and blood products, mother-to-child transmission and sexual transmission. The disease is not the same, generally hepatitis E does not become chronic, while hepatitis B is more chronic. China is a large country of hepatitis B, most of them are infected in infancy, and some patients will progress to liver cirrhosis and liver cancer. Four, the treatment plan is different, hepatitis E is mainly used symptomatic treatment, chronic hepatitis B the most fundamental treatment is antiviral therapy.