Sulpiride can be taken for a long time, especially for patients with schizophrenia must take long-term medication treatment. Because schizophrenia is a very easy to relapse disease, and is a lifelong disease, only adhere to the drug treatment, long-term drug treatment, can effectively control the disease, while preventing relapse. Sulpiride, as a very good antipsychotic drug, can not only treat schizophrenia, but also for the relief of negative symptoms, such as reluctance to meet people, laziness, passivity, emotional indifference, slow thinking, etc., has a very good therapeutic effect, and can also treat depression or anxiety, obsessive-compulsive disorder and other problems. However, these medications must be taken under the guidance and arrangement of the doctor in person, especially the arrangement of taking the medication as prescribed by the doctor. If they are used for a long period of time, the liver and kidney functions should also be checked regularly.