Recently, huzhou little boy after being bitten by a dog, parents immediately took him to the hospital to play the vaccine, but later the child is still rabies morbidity and death. As a disease with 100% mortality after the onset of the disease, the only safe and effective way is to vaccinate, but why there are still cases of morbidity after vaccination of chicken, as long as there are the following reasons: 1, there is no timely and effective treatment of wounds. Research results show that the rabies virus stays at the wound for about 12 h, and then invades the tissues of the organism. Therefore, WHO recommends that wounds be thoroughly rinsed and cleaned with soap and water, detergent, povidone-iodine disinfectant, or other solutions that can kill the rabies virus for more than 15 minutes immediately after contact with an animal suspected of having rabies. 2. Failure to use anti-rabies virus serum or immune globulin as required. 3.Injecting rabies vaccine and serum in a timely manner, throughout the process, and in the main amount. Failure to meet the above requirements will easily fail to achieve the immunization effect. 4.Medical institutions do not store the vaccine in an environment of 2-8 degrees Celsius as required. 5.After vaccination, drinking a lot of alcohol, strenuous exercise, drinking strong tea, eating stimulating food, will affect the effect of vaccination. 6.Fake vaccine!