The establishment of a treatment plan for nephritis is largely based on the type of pathological damage to the kidney. The treatment will be different for different types of nephritis. Generally speaking, the treatment of nephritis includes several aspects: 1) control the systemic symptoms caused by nephritis; 2) reduce and improve the inflammatory damage of kidney tissues; 3) prevent or correct comorbidities or complications. The core of kidney disease treatment is to prevent the deterioration of kidney function rather than simply improving proteinuria or hematuria. 1.Control the systemic symptoms caused by nephritis During the attack of nephritis, it often shows swelling, weakness, hypertension, oliguria, and hematuria of the naked eye, etc. Some patients also have symptoms of the digestive tract, such as nausea, vomiting, and anorexia. The reason for these symptoms is mainly related to the decrease of protein concentration in the blood caused by a large loss of protein in the body through urine. For mild edema, it can be controlled by low-salt diet and water restriction or appropriate diuresis; while for severe edema, in addition to the above measures, human albumin, plasma and related substitutes can be imported to increase plasma osmolality to enhance diuretic response. 2.Control the inflammatory response in the kidney Immunosuppressants can inhibit or reduce the inflammatory response in the kidney tissue, improve proteinuria and hematuria, and relieve the kidney lesions transiently. Commonly used immunosuppressants are glucocorticoids (prednisone), some drugs that inhibit the anabolism of inflammatory cells (cyclophosphamide, azathioprine, mycophenolate and some monoclonal antibodies, etc.); some traditional Chinese medicines (such as Leigengteng) also have a strong immunosuppressive effect. It should be noted that these drugs have strong side effects or side reactions, dosage and use time should be strictly controlled, do not use blindly without purpose. 3, reduce the workload of the kidney When the kidney is diseased, the working pressure of the glomerulus (glomerular perfusion pressure) rises significantly. Effectively reducing glomerular work pressure can improve proteinuria and slow down the progress of the disease. Commonly used drugs include renin-angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists. These drugs need to be used early and maintained for a long time to maximize their efficacy. Both converting enzyme inhibitors and angiotensin II receptor antagonists can also effectively lower systemic blood pressure, so they are especially suitable for patients with massive proteinuria and hypertension. For patients with normal blood pressure and patients with severe renal insufficiency, blood pressure and renal function need to be monitored. 4, prevention of comorbidities nephritis patients are very easy to combine infection, blood clots, malignant hypertension and other comorbidities, in the process of kidney disease treatment need to pay attention to control blood pressure, correct hyperlipidemia, hyperviscosity, improve their own physical condition. Finally, it is worth emphasizing that medication is only a small part of the treatment process of kidney disease, the most important part of the treatment process of chronic kidney disease is to find the cause and aggravating factors of the disease (poor living habits and diet), to enhance physical fitness, and to avoid some artificial factors that induce or strengthen the disease (such as abuse of antibiotics, intravenous infusions).